Endocrine Abstracts

Aim: Previous studies have shown that diabetes associated antibodies are present in 85–90% of patients with Type 1 diabetes. NICE guidelines do not suggest routine use of antibodies screening at initial presentation. The aim of our study was to identify the incidence of antibody positivity in our centre and also review the clinical profile of children diagnosed with diabetes who were antibodies negative.Method: Retrospective case notes review of 243...

Children and adolescents with Type 1 Diabetes Mellitus (T1DM) are at increased risk for developing other autoimmune diseases. We are presenting this rare association of tubulo-interstitial nephritis and uveitis (TINU) with severe hypercalcaemia and type 1 DM. 12 years old girl, with Type 1 Diabetes for 5 years presented with 4 months history of weight loss, abdominal pain, nausea, tiredness, anorexia and recurrent hypoglycaemias. Her HbA1c levels was 38 mmol/mol (5.6%). She wa...

Background: WHO has recommended that adults of South Asian (SA) ethnicity need to have lower body mass index (BMI) cut-off to define overweight and obesity compared to White Caucasians (WC). The background for this is the increasing evidence that obesity-related morbidities are much higher at a lower BMI among SA compared to WC adults.Objective: The aim of our study was to evaluate differences in measures of insulin sensitivity amongst children and adole...